Grzegorz Bulaj Selected Research

Galanin Receptors (Galanin Receptor)

7/2017	Preclinical Analgesic and Safety Evaluation of the GalR2-preferring Analog, NAX 810-2.
1/2017	Preclinical evaluation of intravenous NAX 810-2, a novel GalR2-preferring analog, for anticonvulsant efficacy and pharmacokinetics.
3/2016	The anticonvulsant action of the galanin receptor agonist NAX-5055 involves modulation of both excitatory- and inhibitory neurotransmission.
1/2015	Analgesic properties of a peripherally acting and GalR2 receptor-preferring galanin analog in inflammatory, neuropathic, and acute pain models.
2/2010	Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic delivery.
4/2009	Developing novel antiepileptic drugs: characterization of NAX 5055, a systemically-active galanin analog, in epilepsy models.
3/2009	Structural requirements for a lipoamino acid in modulating the anticonvulsant activities of systemically active galanin analogues.

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Grzegorz Bulaj Research Topics

Disease

15	Pain (Aches) 01/2022 - 06/2006
15	Epilepsy (Aura) 01/2019 - 03/2009
12	Seizures (Absence Seizure) 01/2018 - 12/2008
5	Chronic Disease (Chronic Diseases) 01/2022 - 01/2014
5	Neoplasms (Cancer) 01/2019 - 01/2008
4	Nervous System Diseases (Neurological Disorders) 01/2019 - 01/2014
4	Neuralgia (Stump Neuralgia) 03/2016 - 01/2014
2	Hyperglycemia 07/2017 - 01/2017
2	Schizophrenia (Dementia Praecox) 01/2016 - 01/2015
2	Acute Pain 01/2015 - 01/2015
1	Opioid-Related Disorders (Opiate Addiction) 01/2022
1	Drug-Related Side Effects and Adverse Reactions 01/2021
1	COVID-19 01/2021
1	Human Influenza (Influenza) 01/2021
1	Virus Diseases (Viral Diseases) 01/2021
1	Edema (Dropsy) 01/2019
1	Hyperalgesia 07/2017
1	Cognitive Dysfunction 07/2017
1	Major Depressive Disorder (Major Depressive Disorders) 01/2017
1	Osteoarthritis 01/2016
1	Fatigue 10/2015
1	Spinal Cord Injuries (Spinal Cord Injury) 07/2014
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2014
1	Partial Epilepsies (Epilepsy, Partial) 04/2009
1	Cardiovascular Diseases (Cardiovascular Disease) 08/2008
1	Paralysis (Palsy) 02/2008
1	Mental Disorders (Mental Disorder) 01/2008
1	Infarction (Infarctions) 08/2005
1	Myocardial Ischemia (Ischemic Heart Diseases) 08/2005

Drug/Important Bio-Agent (IBA)

11	GalaninIBA 01/2019 - 12/2008
9	Anticonvulsants (Antiepileptic Drugs)IBA 01/2016 - 03/2009
7	Pharmaceutical PreparationsIBA 01/2021 - 01/2011
7	Analgesics (Analgesic Drugs)IBA 01/2019 - 04/2007
7	Galanin Receptors (Galanin Receptor)IBA 07/2017 - 03/2009
7	NeuropeptidesIBA 01/2015 - 12/2008
6	Peptides (Polypeptides)IBA 05/2012 - 08/2005
3	CarrageenanIBA 01/2019 - 02/2013
3	Formaldehyde (Formol)FDA Link 07/2017 - 05/2012
3	Sodium Channels (Sodium Channel)IBA 06/2010 - 06/2006
2	NAX 5055IBA 01/2019 - 04/2009
2	NAX 810-2IBA 07/2017 - 01/2017
2	Voltage-Gated Sodium ChannelsIBA 03/2016 - 07/2014
2	Neuropeptide YIBA 01/2013 - 04/2011
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 06/2012 - 06/2012
2	NeurotensinIBA 04/2011 - 03/2009
2	VenomsIBA 03/2009 - 01/2008
1	Buprenorphine (Subutex)FDA LinkGeneric 01/2022
1	Opiate AlkaloidsIBA 01/2022
1	CannabidiolIBA 01/2019
1	Ibuprofen (Motrin)FDA LinkGeneric 01/2019
1	Levetiracetam (Keppra)FDA LinkGeneric 01/2019
1	zaleplon (Sonata)FDA LinkGeneric 01/2018
1	Growth Hormone (Somatotropin)IBA 07/2017
1	Insulin (Novolin)FDA Link 07/2017
1	Antidepressive Agents (Antidepressants)IBA 01/2017
1	ConvulsantsIBA 03/2016
1	Thioctic Acid (Lipoic Acid)IBA 01/2016
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2016
1	CurcuminIBA 01/2016
1	theanineIBA 01/2016
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2016
1	ResveratrolIBA 01/2016
1	Neurotensin Receptors (Neurotensin Receptor)IBA 01/2015
1	S(8)IBA 06/2012
1	AS 8IBA 05/2012
1	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 04/2011
1	Dynorphins (Dynorphin)IBA 04/2011
1	LeptinIBA 01/2011
1	LigandsIBA 06/2010
1	Type 2 Galanin ReceptorIBA 04/2009
1	Ion Channels (Ion Channel)IBA 08/2008
1	Conotoxins (Conotoxin)IBA 01/2008
1	Local AnestheticsIBA 06/2006
1	Mollusk VenomsIBA 08/2005

Therapy/Procedure

9	Therapeutics 01/2022 - 10/2007
5	Drug Therapy (Chemotherapy) 01/2022 - 01/2014
3	Analgesia 01/2019 - 02/2013
1	Ligation 07/2017
1	Meditation 01/2017
1	Intravenous Administration 01/2017
1	Precision Medicine 01/2016
1	Oral Administration 05/2012